Quercetin protects against 17α-methyltestosterone induced hepatocardiac toxicity: Roles of lipid metabolism, oxidative stress, and inflammation

Key Points

• Quercetin significantly protects against hepatotoxicity, reducing oxidative stress and inflammation.
• In animal models, treatment with quercetin resulted in a marked decrease in markers of liver damage.
• The analysis highlights the impact of lipid metabolism alterations as a response to 17α-methyltestosterone administration.
• These findings underlie the potential for dietary interventions in managing hepatocardiac toxicity.