Palladium-catalyzed decarboxylative 4 + 2 cycloaddition of δ-vinylvalerolactones for the synthesis of spirocyclohexane compounds

Key Points

• This reaction enables the synthesis of various spirocyclohexane compounds through an efficient cycloaddition process.
• Palladium acts as a catalyst to generate all-carbon π-allylpalladium species in situ, which are crucial for the reaction.
• The use of α,α-diester-δ-vinylvalerolactones as a precursor allows access to diverse molecular structures.
• This innovative method may provide valuable strategies for compound synthesis in organic chemistry.