Exosomal miR-1 modulates Cx43 expression through Tbx18 in cultured atrial fibroblasts under rapid electrical stimulation, providing insights into cardiac remodeling and potential targets for tachyarrhythmia.
In HCF-aa under RES, miR-1 and Tbx18 regulated Cx43 expression, with miR-1 modulating Cx43 through Tbx18. These findings provide insights into the molecular mechanisms of cardiac remodeling and offer potential therapeutic targets for treating tachyarrhythmia.
Chuang et al. (Thu,) studied this question.