STOML2 is not essential for spermatogenesis and male fertility in mice

Key Points

• No essential function of STOML2 in spermatogenesis was observed, leading to normal sperm production.
• A genetic knockout of STOML2 revealed no adverse effects on male fertility metrics.
• The absence of STOML2 did not impact testosterone levels, indicating its non-critical role in hormone regulation.
• Findings may highlight the existence of compensatory mechanisms for male reproductive health.