Quantification of three progestogens in serum from polycystic ovary syndrome patients by LC-MS/MS based on magnetic solid phase extraction and quaternary ammonium oxime derivatization | Synapse
March 3, 2026
Quantification of three progestogens in serum from polycystic ovary syndrome patients by LC-MS/MS based on magnetic solid phase extraction and quaternary ammonium oxime derivatization
Key Points
Findings reveal significant levels of progestogens in serum samples from patients with polycystic ovary syndrome.
Quantification demonstrates accurate measurement using liquid chromatography coupled with tandem mass spectrometry.
Assessment applies magnetic solid phase extraction and quaternary ammonium oxime derivatization for enhanced sensitivity.
Results support potential clinical applications in diagnosing and monitoring hormonal imbalances in affected individuals.