Interruptive versus Non-Interruptive Reminders for Statin tHerApy in Primary Care (INIRSHA-PC): protocol and statistical analysis plan for a randomised clinical trial

Key Points

• Interruption strategies may improve adherence to statin therapy among patients in primary care, suggesting a more efficient reminder system.
• The statistical analysis plan will guide evaluation of adherence metrics over time in participants receiving different reminder types.
• Randomised clinical trial protocol studies the impact of reminder styles on medication adherence, aiming for better health outcomes.
• Results may support the efficacy of tailored reminder systems for chronic medication adherence in primary care settings.