March 3, 2026Open Access

Construction and Validation of a Clinical Pregnancy Outcome Prediction Model for Infertility Treatment Using IVF/ICSI: A Retrospective Study Based on 11,449 Cases

Key Points

Clinical pregnancy outcomes depend on various factors, including male and female ages and antral follicle count.
Notable metrics include the number of usable embryos and high-quality blastocysts, contributing significantly to decision-making.
Retrospective analysis based on 11,449 cases highlights essential elements in IVF/ICSI treatment.
The prediction model potentially enhances clinical decision support in infertility management, guiding treatment options effectively.

Abstract

This study identified key factors influencing clinical pregnancy outcomes following IVF/ICSI treatment, including male age, antral follicle count (AFC), Day 3 follicle-stimulating hormone (FSH) level, endometrial thickness, female age, number of usable embryos, number of high-quality blastocysts, and number of embryos transferred. This model serves as a scientifically sound decision-support tool for clinicians in the management of infertility treatment with IVF/ICSI.

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Cite This Study

Guo et al. (Wed,) studied this question.

synapsesocial.com/papers/69a75c47c6e9836116a24fe4 https://doi.org/https://doi.org/10.3389/fendo.2026.1594250

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