Mitotic entry: Bora takes Polo to Aurora, and gives them a hug

Key Points

• Bora plays a crucial role in mitotic entry, facilitating interactions with Polo and Aurora—essential for proper cell division.
• In particular, Bora's interaction with Polo demonstrates a significant regulatory role in mitotic signaling pathways; average ratio measures show a striking correlation.
• Cell cycle analysis through live imaging techniques confirms the dynamic interactions between Bora, Polo, and Aurora during mitotic entry phases.
• These findings highlight essential molecular interactions, indicating potential therapeutic targets for cancer treatment, requiring further examination in vivo.