The protective effect of neurointerventional recanalization on the neurovascular unit in acute ischemic stroke and its correlation with serum GFAP and NfL levels

Key Points

• Successful recanalization mitigates axonal injury and promotes neurovascular unit integrity, enhancing recovery.
• Serum neurofilament light chain (NfL) and glial fibrillary acidic protein (GFAP) are promising biomarkers for stroke prognosis.
• The association between recanalization and reduced neuroinflammation indicates potential therapeutic avenues for acute ischemic stroke.
• Implications for clinical practice suggest that monitoring NfL and GFAP levels may help personalize stroke treatment strategies.