Hyper-expression of functional human basic fibroblast growth factor 2 in Escherichia coli

Key Points

• Functional human basic fibroblast growth factor 2 was expressed at high levels in Escherichia coli, achieving significant yield.
• The study reported a notable increase in protein yield compared to traditional expression systems, reaching levels above 1 gram per liter.
• Recombinant protein techniques were employed to optimize protein expression in a bacterial system, enhancing the overall yield.
• Such findings highlight the potential for bacterial systems in producing therapeutic proteins, requiring further real-world application studies.