PSMA-RADS 2.0: clinical validation and technical considerations for prostate-specific membrane antigen positron emission tomography/computed tomography image interpretation

Key Points

• PSMA-RADS 2.0 provides a reliable framework for interpreting PET/CT images, improving treatment decisions.
• The proposed PSMA-RADS-5T sub-classification may enhance clinical utility by monitoring remission and disease progression.
• Further refinement of post-treatment categorization is needed, especially for accurate lymph node differentiation.
• Implementation of PSMA-RADS improvements may support better patient management in clinical settings.