Mechanisms and safety evaluation of stir-fried atractylodis macrocephalae rhizoma with aurantii fructus in the treatment of inflammatory bowel disease: a study based on organ-on-a-chip model | Synapse
March 3, 2026Open Access
Mechanisms and safety evaluation of stir-fried atractylodis macrocephalae rhizoma with aurantii fructus in the treatment of inflammatory bowel disease: a study based on organ-on-a-chip model
Key Points
Active components in stir-fried atractylodis macrocephalae rhizoma show promise in treating inflammatory bowel disease.
Safety assessment reveals positive outcomes in organ-on-a-chip models, indicating reliability of findings.
Evaluation of mechanisms highlights the therapeutic potential of the herbal remedy in gastrointestinal conditions.
Further research on this model could enable novel treatment approaches for inflammatory bowel disease.
Abstract
In conclusion, this study elucidates the active components and mechanisms of SFALCA in treating IBD and assesses its safety, providing a reliable in vitro platform for future therapeutic strategies.