A novel biomimetic nanovesicle-based microextraction combined with high performance liquid chromatography for the determination of flavonoids in Huangqisan

Key Points

• Flavonoids were accurately determined using novel biomimetic nanovesicles, enhancing extraction efficiency.
• The method achieved a strong performance with high sensitivity and specificity for flavonoid detection.
• Microextraction combined with high performance liquid chromatography was employed to assess flavonoid levels.
• This innovation supports advanced extraction techniques for natural product analysis, urging wider application.