Deciphering RNA and protein expression discordance identifies TOP2A as a prognostic biomarker and potential therapeutic target in lung adenocarcinoma

Key Points

• TOP2A serves as a promising prognostic biomarker for lung adenocarcinoma, highlighting its relevance in patient outcomes.
• A correlation between TOP2A expression and disease progression highlights its potential role in treatment decisions.
• Analysis of RNA and protein expression discordance indicates the significance of TOP2A in targeting therapeutic strategies.
• Identifying TOP2A as a target may enable better management of lung adenocarcinoma, increasing survival prospects.