N-acetyl-cysteine alleviates nandrolone decanoate-induced hippocampal cell apoptosis in rats via reversing protein expressions of S1P1, Akt and FOXO3a signaling pathway

Key Points

• N-acetyl-cysteine successfully decreases hippocampal cell apoptosis, pointing to potential therapeutic effects.
• Protein expression levels of S1P1, Akt, and FOXO3a are significantly reversed with N-acetyl-cysteine treatment.
• The study employs a control group for comparison of treatment effects in rat models exposed to nandrolone decanoate.
• The findings highlight the need for further exploration of this intervention in preventing neuronal damage.