Inverted Sinonasal Papilloma: Pheno-endotyping and Predictive Markers of Recurrence and Malignancy – A Systematic Review

Key Points

• Recurrence rates are notably high in inverted sinonasal papilloma cases, indicating a significant clinical challenge.
• Key predictive markers for recurrence include specific genetic mutations and histological features observed in affected tissues.
• Systematic review incorporates various studies on phenotyping and outcomes associated with inverted sinonasal papilloma across multiple settings.
• Identifying predictive markers may enable improved patient management and tailored therapeutic strategies, emphasizing the need for further research.