Thermosensitive spray-gel oxaliplatin delivery system for antitumor efficacy and mechanistic study in a mouse subcutaneous xenograft model

Key Points

• Antitumor efficacy is enhanced with a thermosensitive oxaliplatin delivery system.
• A significant decrease in tumor size was observed in treated mice, particularly after heating.
• Assessment utilized a mouse subcutaneous xenograft model to evaluate treatment effects.
• This approach may enable better targeting of tumors while minimizing side effects, though mouse model studies require further validation.