Efficacy effects of fecal microbiota transplantation on depressive symptoms: a meta-analysis based on randomized controlled trials

Key Points

• Fecal microbiota transplantation (FMT) shows limited efficacy for reducing depressive symptoms overall,
• Observations indicate FMT may be more effective in patients with confirmed depression, revealing a need for more research.
• Meta-analysis of randomized controlled trials highlights the preliminary nature of current results on FMT's antidepressant effect.
• The findings imply further studies are necessary to definitively establish FMT's role in treating depression.