Maternal dibutyl benzene-1,2-dicarboxylate exposure accelerates bone marrow mesenchymal stem cells senescence to induce skeletal retardation in male offspring mice | Synapse
March 3, 2026
Maternal dibutyl benzene-1,2-dicarboxylate exposure accelerates bone marrow mesenchymal stem cells senescence to induce skeletal retardation in male offspring mice
Key Points
Skeletal retardation occurs in male offspring mice exposed to dibutyl benzene-1,2-dicarboxylate, indicating significant developmental effects.
The study reports a notable increase in bone marrow mesenchymal stem cell senescence among exposed offspring, suggesting accelerated aging.
Analysis of maternal exposure to the chemical indicates a direct link to negative skeletal development in offspring through stem cell modulation.
Highlighting the need for further research, these findings suggest potential health risks associated with maternal exposure to dibutyl benzene-1,2-dicarboxylate.