Circulating Tumor DNA as a Biomarker for Recurrence After Curative Resection of Colorectal Cancer Liver Metastases: A Systematic Review and Meta-Analysis | Synapse
March 3, 2026
Circulating Tumor DNA as a Biomarker for Recurrence After Curative Resection of Colorectal Cancer Liver Metastases: A Systematic Review and Meta-Analysis
Key Points
Circulating tumor DNA is a promising biomarker for detecting recurrence after colorectal cancer liver metastases resection.
The analysis revealed a significant association between circulating tumor DNA levels and recurrence risk, with a pooled hazard ratio of 2.5.
Systematic review and meta-analysis of existing studies address the utility of circulating tumor DNA in colorectal cancer contexts.
This study emphasizes the need for further validation in diverse populations to solidify its clinical application.