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Depression and cognition in adolescents: A comparison of cross-sectional and longitudinal effects | Synapse
March 3, 2026
Depression and cognition in adolescents: A comparison of cross-sectional and longitudinal effects
SK
Sarah Kuburi
Centre for Addiction and Mental Health
AS
Anett Schumacher
ET
Eric Tu
Hospital for Sick Children
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Key Points
Cognitive deficits associated with depression are evident in adolescents over time.
Results highlight differences between cross-sectional and longitudinal impacts on mental health outcomes.
Analysis of neuropsychological assessments provides insight into cognitive decline linked with depression.
Further investigation is needed to clarify causal relationships and treatment modalities.
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Kuburi et al. (Thu,) studied this question.
synapsesocial.com/papers/69a75df7c6e9836116a284a2
https://doi.org/https://doi.org/10.1016/j.jad.2026.121282