Computed tomography-based tumoral and peritumoral radiomics models for preoperative prediction of the spread through air spaces in patients with clinical stage I pure solid invasive lung adenocarcinoma: a multicenter study

Key Points

• Preoperative prediction of STAS status was significantly enhanced by integrating radiomics characteristics and clinical factors.
• The study revealed a strong correlation between peritumoral features and STAS status, suggesting they are critical indicators.
• Utilization of computed tomography provided detailed imaging to inform tumor spread predictions effectively.
• Integration of clinical factors with radiomic data may offer a more accurate approach for patient management.

Abstract