Acute low-dose benzoapyrene exposure induces neurodegenerative syndrome in cyp1a low-expression zebrafish: A novel living Bioindicator for dioxin-like environmental pollutants

Key Points

• Neurodegenerative syndrome develops in zebrafish following low-dose exposure to benzo[a]pyrene, indicating significant neurotoxicity.
• The study identifies cyp1a expression levels as a critical factor influencing the impact of benzo[a]pyrene on the zebrafish model.
• Assessment using zebrafish bioindicators highlights their potential utility in monitoring dioxin-like environmental pollutants.
• The research supports using zebrafish for ecological risk assessments, although further validation is needed for broader applications.