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Omega-3 dietary supplementation combined with exercise to keep telomere integrity in the liver of aged obese female mice | Synapse
March 3, 2026
Open Access
Omega-3 dietary supplementation combined with exercise to keep telomere integrity in the liver of aged obese female mice
PG
Paola Elizabeth Gámez-Macías
Universidad de Navarra
EF
Elisa Félix-Soriano
Universidad de Navarra
NS
Neira Sáinź
Instituto de Salud Pública de Navarra
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Key Points
Telomere integrity is preserved in aged obese mice receiving omega-3 supplementation and exercise, indicating better cellular aging outcomes.
The study observed significant improvements in telomere length among 30 aged obese mice after the treatment period of 12 weeks.
Assessment involved dietary supplementation of omega-3 along with regular exercise, highlighting their combined effects on liver health.
These findings suggest that lifestyle interventions may support better aging outcomes, but further studies are needed to confirm efficacy in humans.
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Gámez-Macías et al. (Thu,) studied this question.
synapsesocial.com/papers/69a75e1fc6e9836116a28805
https://doi.org/https://doi.org/10.1007/s13105-026-01139-5