Efficacy and safety of time-of-day infusion of pemetrexed plus platinum for patients with advanced non-small cell lung cancer: a retrospective cohort study

Key Points

• Morning infusion of pemetrexed plus platinum enhances progression-free survival (PFS) in patients.
• The study indicates a notable improvement in efficacy with this time-of-day administration.
• Retrospective cohort study analyzed outcomes for patients with advanced non-small cell lung cancer (NSCLC).
• The findings suggest chrono-chemotherapy may lead to better individualized treatment strategies.