Is the assessment of central vein sign on FLAIR alone reliable compared to FLAIR* in a diagnostic cohort?
Diagnostic cohort
Assessment of central vein sign (CVS) on FLAIR alone
FLAIR* (susceptibility-sensitive sequences)
Reliability and clinical usefulnesssurrogate
Assessment of the central vein sign requires susceptibility-sensitive sequences (FLAIR*) rather than FLAIR alone to be clinically useful.
Assessment of CVS on FLAIR alone is unreliable and requires susceptibility-sensitive sequences to be clinically useful.
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Karlo Toljan
Moein Amin
Lynn Daboul
European Journal of Radiology
National Institutes of Health
University of Pennsylvania
Cleveland Clinic
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Toljan et al. (Thu,) studied this question.
www.synapsesocial.com/papers/69a75e41c6e9836116a28af4 — DOI: https://doi.org/10.1016/j.ejrad.2026.112707