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Monocyte-derived macrophages promote retinal damage after ischemic stroke via IL-1β-dependent mechanism | Synapse
March 3, 2026
Monocyte-derived macrophages promote retinal damage after ischemic stroke via IL-1β-dependent mechanism
HL
Hong-Bin Lin
JZ
Jinyu Zhang
Zhejiang Chinese Medical University
ML
Meng Li
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Key Points
Retinal damage occurs after ischemic stroke, highlighting the role of inflammation.
IL-1β levels were significantly elevated, showing a clear link to retinal injury.
This observational analysis focuses on the inflammatory response in ischemic models involving macrophages.
Findings suggest monocyte-derived macrophages may contribute to retinal damage, calling for targeted therapies.
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Lin et al. (Fri,) studied this question.
synapsesocial.com/papers/69a75ee8c6e9836116a29edc
https://doi.org/https://doi.org/10.1016/j.expneurol.2026.115676