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A case of Creutzfeldt-Jakob disease mimicking autoimmune encephalitis: A diagnostic pitfall | Synapse
March 3, 2026
A case of Creutzfeldt-Jakob disease mimicking autoimmune encephalitis: A diagnostic pitfall
SY
Soyeon Yoon
HK
Hyung Jun Kim
Key Points
Creutzfeldt-Jakob disease can present similarly to autoimmune encephalitis, complicating diagnosis.
A notable case revealed misinterpretation of symptoms, leading to delays in appropriate treatment.
Diagnostic imaging confirmed neurological abnormalities but did not clarify the underlying disease mechanism.
Highlights the need for awareness of atypical presentations to avoid misdiagnosis and ensure timely intervention.
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Yoon et al. (Mon,) studied this question.
synapsesocial.com/papers/69a75f14c6e9836116a2a33b
https://doi.org/https://doi.org/10.1016/j.jns.2025.124660