The surgical treatment for gastrointestinal stromal tumor of the stomach

Surgical resection with negative margins is a major standard of care for gastrointestinal stromal tumor (GIST) of stomach. Currently, multiple studies have developed and described endoscopic and laparoscopic approaches for treating patients with gastric GIST that demonstrate advantages of using intraluminal and intraperitoneal procedures during the same surgical period. Non-exposed endoscopic wall-inversion surgery (NEWS) for patients with gastric GIST is a novel, minimally invasive surgical technique that may aid in complete resection using endoscopy and laparoscopy methods, removing the whole layer of the gastric wall and the entire tumor, with minimizing risk of peritoneal contamination or tumor spread to the peritoneum.