Effects of alcohol abstinence on a rapid recovery of social cognition

Abstract: We explored the recovery of socio-cognitive functioning in a SAUD (Severe Alcohol Use Disorder) sample before and after two weeks of abstinence. At T1, the SAUD group was significantly more sensitive to external interferences and showed poorer self–other distinction abilities compared to healthy controls. After abstinence, they reached performance levels comparable to the control group. We further examined patients’ individual trajectories over time. Context: SAUD is associated with socio-cognitive impairments, particularly in perspective-taking abilities, which are crucial for social functioning. These abilities remain poorly investigated. Goal: This study aims to examine perspective-taking in SAUD patients compared to healthy controls, focusing on self-other distinction and self-other priority indices, and to evaluate changes in pre- and post-withdrawal treatment. Method: Perspective-taking indices were measured in SAUD patients and matched controls before and after a withdrawal intervention. Results: Results indicate poorer self-other distinction before withdrawal compared to controls, but significant improvements following treatment. When examining individual trajectories of recovery, results show that 50% of the SAUD patients improve to the extent of being no longer different than the HC after abstinence. Conclusion: These findings show altered perspective-taking in SAUD and suggest that withdrawal treatment contributes to the recovery of socio-cognitive functioning. Yet, important individual differences in recovery profiles remain to be further investigated.