Author Correction: Regulation of nucleotide metabolism by mutant p53 contributes to its gain-of-function activities

Key Points

• Mutant p53 enhances nucleotide metabolism, increasing its gain-of-function activities with significant effects on cell growth.
• Key evidence includes alterations in metabolic pathways linked to mutant p53, affecting nucleic acid synthesis and cell proliferation.
• Analysis of molecular pathways indicates that mutant p53 directly influences nucleotide metabolism, leading to oncogenic effects.
• These findings highlight the potential for targeting nucleotide metabolism in therapies against cancers driven by mutant p53.