Catastrophic Consequences of Bacillus Cereus–Contaminated Hematopoietic Stem Cells: Hemolytic Transfusion Reaction, Septic Shock, and Adaptive GVHD Prophylaxis in a Pediatric Allogeneic Transplant

Key Points

• Patients experienced hemolytic transfusion reactions and septic shock due to bacillus cereus contamination.
• Hemolytic transfusion reactions were reported in pediatric patients receiving stem cell transplants and correlated with contamination incidents.
• Observational analysis highlights the importance of bacterial safety measures in hematopoietic stem cell procedures.
• These findings emphasize the need for stringent protocols to prevent contamination and protect vulnerable populations.