Factors Associated with Acute and Chronic Graft-Versus-Host Disease after Unrelated Donor Hematopoietic Cell Transplantation Using Posttransplant Cyclophosphamide-Based GVHD Prophylaxis

Key Points

• Graft-versus-host disease occurs in both acute and chronic forms, impacting recovery after transplantation.
• Key participant characteristics, including donor type and immunosuppression protocol, affect GVHD incidence.
• Analysis focuses on data following unrelated donor hematopoietic cell transplantation to identify risk factors for GVHD.
• Findings highlight the need for tailored prophylaxis strategies to improve patient outcomes post-transplant.