An injectable dual-functional biomimetic system based on carboxymethyl chitin sulfate and hyaluronic acid for viscosupplementation and sustained triamcinolone acetonide release in osteoarthritis therapy

Key Points

• Viscosupplementation may enhance joint lubrication and pain relief in osteoarthritis patients, leading to improved mobility.
• The injectable system showcases a sustained release of triamcinolone acetonide, significantly affecting treatment outcomes.
• Analysis using a dual-functional biomimetic system highlights its potential for use in osteoarthritis therapies.
• This approach may enable new treatment strategies for osteoarthritis management, addressing unmet medical needs.