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Thiotepa-Based Conditioning Regimens for Patients with Central Nervous System Lymphoma Undergoing Autologous Stem Cell Transplant | Synapse
March 3, 2026
Thiotepa-Based Conditioning Regimens for Patients with Central Nervous System Lymphoma Undergoing Autologous Stem Cell Transplant
JS
Jarrod T. Smith
VP
Vivek Patel
Ambedkar University Delhi
SB
Shakthi Bhaskar
Tennessee Oncology
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Key Points
Effectiveness of thiotepa-based conditioning regimens significantly enhances transplant success rates.
In patients with central nervous system lymphoma, the use of thiotepa shows a notable improvement in overall survival rates.
Observational analysis reveals that conditioning regimens incorporating thiotepa may lead to fewer complications post-transplantation.
Further studies are necessary to explore the long-term effects of thiotepa in this patient population.
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Cite This Study
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Smith et al. (Sun,) studied this question.
synapsesocial.com/papers/69a76063c6e9836116a2d126
https://doi.org/https://doi.org/10.1016/j.jtct.2025.12.200