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A Multi-Center, phase 1/2 Trial of AlloNK® Cell Therapy ± Rituximab in Patients with Relapsed or Refractory Non-Hodgkin Lymphoma | Synapse
March 3, 2026
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A Multi-Center, phase 1/2 Trial of AlloNK® Cell Therapy ± Rituximab in Patients with Relapsed or Refractory Non-Hodgkin Lymphoma
UF
Umar Farooq
University of Iowa
AM
Amitkumar Mehta
University of Alabama at Birmingham Hospital
ED
Erin A. Dean
University of Florida
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Key Points
AlloNK cell therapy shows promise for relapsed or refractory non-hodgkin lymphoma patients, enhancing treatment options.
The trial reports improved outcomes with a combination of AlloNK therapy and rituximab for select patients.
Phase 1/2 trial designed to evaluate the safety and efficacy of AlloNK ± rituximab across multiple centers.
These findings indicate a potential breakthrough in therapies for challenging cases of non-hodgkin lymphoma.
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Farooq et al. (Sun,) studied this question.
synapsesocial.com/papers/69a76073c6e9836116a2d319
https://doi.org/https://doi.org/10.1016/j.jtct.2025.12.535