Prevalence of Atypical Chronic Graft-Versus-Host Disease Manifestations According to NIH Provisional Diagnostic Criteria

Key Points

• Atypical manifestations of chronic graft-versus-host disease were identified under NIH criteria, highlighting diagnostic variability.
• Findings showed that more than 30% of cases exhibited atypical features, complicating their management and treatment.
• Analysis followed NIH provisional diagnostic criteria to identify atypical manifestations in a diverse patient cohort.
• These findings suggest a need for revising existing diagnostic criteria to better capture the spectrum of chronic graft-versus-host disease.