Does stress perfusion cardiac magnetic resonance imaging predict major cardiovascular events and guide management in Kawasaki disease patients with coronary artery aneurysms?
Patients with Kawasaki disease (KD) and coronary artery aneurysms (CAA), including high-risk patients (AHA risk levels 3-4).
Stress perfusion cardiac magnetic resonance imaging (spCMR)
Normal spCMR (absence of inducible perfusion defects)
Major cardiovascular events (MCE) riskhard clinical
Stress perfusion CMR is a valuable prognostic tool for predicting major cardiovascular events and guiding longitudinal surveillance in high-risk Kawasaki disease patients with coronary artery aneurysms.
In KD patients with CAA, inducible perfusion defects on spCMR were associated with increased MCE risk, whereas a normal spCMR in AHA risk levels 3-4 was reassuring. Serial spCMR identified evolving ischemia, guided revascularization decisions, and informed post-intervention management. These findings support the incorporating spCMR into longitudinal surveillance pathway for high-risk KD patients.
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Kiener et al. (Sun,) studied this question.
www.synapsesocial.com/papers/69a7607fc6e9836116a2d4ac — DOI: https://doi.org/10.1016/j.jocmr.2025.102671
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Journal of Cardiovascular Magnetic Resonance
Texas Children's Hospital
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