Neutrophils in glioblastoma: orchestrators of the tumor microenvironment and immune evasion

Key Points

• Neutrophils significantly influence the tumor microenvironment and promote immune evasion in glioblastoma.
• The profound interaction between neutrophils and tumor cells triggers specific inflammatory pathways crucial for tumor progression.
• This assessment highlights the role of immune cells, particularly neutrophils, in glioblastoma pathophysiology and treatment resistance.
• This work supports new therapeutic approaches targeting neutrophil activity in glioblastoma, though clinical validation is needed.