Marburg and Sudan virus outbreaks: are we any closer to a pan-filovirus vaccine?

Key Points

• Progress in developing a pan-filovirus vaccine could greatly enhance public health responses, especially in outbreak settings.
• Recent efforts show advances in immunogenicity with promising vaccine candidates that may target both Marburg and Sudan viruses.
• Assessment of outbreak dynamics reveals critical factors influencing vaccine efficacy across different regions and contexts.
• Future initiatives are essential for successful implementation, especially in areas with high prevalence of filovirus outbreaks.