A comprehensive investigation of 4-(4-chlorophenyl)-3-methyl-6,7,8,9-tetrahydroisoxazolo5,4-bquinolin-5(4H)-one as potential anticancer agent: insights from computational and experimental results through crystal structure analysis | Synapse
March 3, 2026
A comprehensive investigation of 4-(4-chlorophenyl)-3-methyl-6,7,8,9-tetrahydroisoxazolo5,4-bquinolin-5(4H)-one as potential anticancer agent: insights from computational and experimental results through crystal structure analysis
Key Points
The compound shows promising anticancer activity against various cancer cell lines, indicating its therapeutic potential.
Key evidence includes a 50% inhibition concentration (IC50) range of 10-30 µM across tested cell lines.
Analysis used crystal structure assessment paired with computational and experimental methods to investigate efficacy.
Findings highlight the compound's potential as a novel anticancer agent, necessitating further clinical investigation.