S100A10 promotes glycolysis and malignant progression of CCA by activating the HK2/ERK signaling pathway

Key Points

• Malignant progression is significantly promoted by S100A10 through glycolysis.
• Activation of the HK2/ERK signaling pathway is critical in this process.
• This analysis highlights the relationship between S100A10 and cancer metabolism.
• Findings could indicate a new approach to treating CCA by targeting S100A10.