The single-particle cryo-EM structures of a bacterial cyanide dihydratase and a fungal cyanide hydratase

Key Points

• Bacterial and fungal cyanide hydratases exhibit distinct structural features, indicating functional specialization.
• High-resolution structures were obtained through single-particle cryo-electron microscopy techniques.
• This analysis contributes to understanding the molecular mechanisms of cyanide metabolism across different organisms.
• Understanding these structures may enable better biotechnological applications targeting cyanide detoxification.