cGAS–STING Signaling Pathway in Urogenital Oncology: Regulation, Resistance, and Routes to Response

Key Points

• The cGAS–STING signaling pathway plays a crucial role in the immune response against tumors.
• Factors influencing resistance to therapies were identified, emphasizing treatment challenges in urogenital cancers.
• Analysis highlights the potential for new therapeutic strategies based on STING pathway modulation.
• Identified mechanisms may enable improved clinical responses in targeted urogenital oncology treatments.