CAP2 promotes skin cutaneous melanoma progression by targeting epithelial-mesenchymal transition-like processes through the TLR4/NF-κB pathway

Key Points

• Melanoma progression is significantly increased in the presence of CAP2, driving epithelial-mesenchymal transition-like processes.
• Key evidence shows that activation of the TLR4/NF-κB pathway correlates with an increase in aggressive cancer characteristics.
• The approach involved assessing cellular processes affected by CAP2 in melanoma cells through signaling pathway analysis.
• These findings highlight CAP2's role in tumor enhancement, suggesting new therapeutic strategies targeting specific pathways.