SEMA3E promotes beige adipocyte differentiation and thermogenesis via β-catenin signaling in mice

Key Points

• Increased thermogenesis is associated with enhanced beige adipocyte differentiation.
• Notably, SEMA3E promotes this differentiation through beta-catenin signaling pathways.
• This study utilized a mouse model to investigate the effects of SEMA3E on adipocyte biology and thermogenesis.
• Findings may enable new therapeutic strategies for obesity and metabolic disorders.