The molecular arms race: Xenophagy, pathogen evasion, and emerging host-directed therapies

Key Points

• Pathogen evasion affects the immune response, complicating treatment outcomes in infectious diseases.
• Xenophagy plays a critical role in recognizing and eliminating pathogens, influencing the efficacy of therapies.
• Assessment of molecular mechanisms employs various techniques to explore the interactions between pathogens and host cells.
• Highlighting the need for innovative host-directed therapies could help combat resistant infections in diverse populations.