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Fecal metabolic signals are associated with changes in microbiota and systemic metabolic pathways in Crohn’s disease | Synapse
March 3, 2026
Open Access
Fecal metabolic signals are associated with changes in microbiota and systemic metabolic pathways in Crohn’s disease
NL
Nina Levhar
RH
Rotem Hadar
Sheba Medical Center
TB
Tzipi Braun
Sheba Medical Center
See all
Key Points
Fecal metabolites are linked with changes in microbiota composition in Crohn’s disease.
Significant alterations were observed in systemic metabolic pathways related to these metabolites.
Analysis included metabolic profiling alongside microbiota assessments in affected individuals.
Findings suggest potential for using these metabolic signals as biomarkers for disease management.
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Levhar et al. (Mon,) studied this question.
synapsesocial.com/papers/69a765bfbadf0bb9e87da45b
https://doi.org/https://doi.org/10.1038/s41598-026-38558-9