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Metformin in gastrointestinal cancers and inflammatory bowel disease: Unraveling its mechanisms and therapeutic applications | Synapse
March 3, 2026
Open Access
Metformin in gastrointestinal cancers and inflammatory bowel disease: Unraveling its mechanisms and therapeutic applications
YL
Yanxi Li
XG
Xingqi Guo
XD
Xinxin Dong
See all
Key Points
Metformin shows promise in therapeutic applications for gastrointestinal cancers and inflammatory bowel disease.
Key evidence includes significant modulation of pathways involved in cancer cell metabolism and inflammation.
The analysis investigates the molecular mechanisms underlying metformin's effects on these diseases.
Findings highlight the need for further exploration of metformin's role in treatment strategies.
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Li et al. (Tue,) studied this question.
synapsesocial.com/papers/69a76601badf0bb9e87db416
https://doi.org/https://doi.org/10.1016/j.isci.2026.114877