Mediolateral neural patterning during gastrulation precedes dorsoventral patterning in chick and frog

Key Points

• Dorsoventral differentiation is influenced by mediolateral patterning during early development.
• Initial functional analysis of hedgehog signaling reveals critical mediolateral interactions.
• This research examines gene expression patterns during gastrulation in chick and frog models.
• Findings imply potential new pathways in embryonic neural differentiation mechanisms.

Abstract